The experimental invasion of rats with Eustrongylides excisus (Nematoda, Dioctophymatidae) larvae during the acute course of infection

Ten laboratory rats were experimentally invaded per os with the Eustrongylides excisus (Jäegerskiold, 1909) nematode larvae (L3–L4) received from Perca fluviatialis (Linnaeus, 1758), caught in water area of Dnipro-Buh Estuary, Ukraine. The aim experimental study was to measure pathogenic effect given parasite on mammals’ organisms by means histological analysis affected organs infected rats. researched animals divided into two groups. experiment lasted 15 days; second group a control group. showed purulent-serous and purulent-fibrinous peritonitis, acute circulatory disorders brain tissues (signs hypoxic-ischemic lesions brainstem form neuronal changes) heart (partial spasm arteries edema interstitial myocardial tissue); pathological changes lungs (acute purulent pneumonia, focal emphysema lungs), liver exudative hepatitis), kidneys shock reaction) intestines serous-purulent enteritis). Formation non-specific granulomas noticed, which contained fragments parasitic larvae. course inflammatory processes noticed; signs systemic response syndrome pronounced distributive vascular leukocytosis studied organs.